James Gallagher reports that the bacteria found in our digestive systems may influence tumor-fighting drugs. A new study suggests that those who have more gut are most likely to benefit from this.
Immunotherapies, a form of treatment, harness the body’s own defense systems in order to fight back against tumors. It has the potential to clear terminal malignancy in some patients. It’s one of the greatest breakthroughs in tumor therapy.
Gut bacteria ‘may help drugs fight cancer’
However, a small study by the University of Texas found those harbouring a more diverse community of gut bugs are more likely to benefit. Cancer Research UK said understanding gut bugs had “great potential”. Read more…
News Medical says that these microorganisms are responsible for improving the treatment response in some melanoma patients. Those who have malignant melanoma appear to respond better to immunotherapy if they have a variety of microbes.
A research presented at the National Cancer Research Institute’s (NCRI) Cancer Conference in Liverpool backs this result. The scientists from University of Texas MD Anderson Cancer Centre had taken samples from patients who were diagnosed with advanced melanoma. 200 mouth and 100 gut samples were examined by the researchers.
Gut Microbiome May Help Improve Immunotherapy Response In Melanoma Patients
Patients with malignant melanoma – whose disease has spread – are more likely to respond to immunotherapy treatment if they had greater diversity in their intestinal bacteria, according to new research presented at the National Cancer Research Institute’s (NCRI) Cancer Conference in Liverpool. Read more…
Steve Duffy from Empr tells us that the analysis depicted an interesting link. The connection may imply that the immune system can be aided further by the microbes when responding to therapeutic drugs.
Lead researcher Jennifer Wargo says though that not all subjects can effectively respond to the immunotherapy drugs and it may be hard to determine which ones can be treated effectively prior to conducting the therapy.
Immunotherapy for Melanoma: Why Gut Bacteria May Be Key
Their analysis showed that those who responded to immunotherapy had more diversity in the types of bacteria found in their gut. Differences were also found in the type of bacteria in the gut of people whose cancer responded vs. those whose cancer did not, whereas no difference was seen in the type of mouth bacteria. Read more…
This is a great approach in the treatment of the condition. It highly suggests that the bacteria can enhance the therapy’s efficacy.
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